1.Nadia Franciscus - Nightmare Creatures
2.Koudelka - Koudelka/Shadow Hearts
3.Clare Redfield - Resident Evil
4.Spyro - Spyro
5.Wallace - Nightmare Creatures II
6.Ash - The Evil Dead
7.Homunculus - Shodow of Memories/Shadow of Destiny
8.Anna Williams - Tekken
9.Rayne - Bloodrayne
10.Jennifer Tate - Primal

Mayu and Mio would have been at the front of the list if Shadow the hedgehog and Sonic Adventure 2 weren't so freaking awesome.
Very few people know what Fatal Frame is, so I'll tell you.  It's a Japanese  game about two Japanese twin sisters who get lost in a haunted village.  There, they find a magic camera that takes pictures of impossible things and can be used to 'kill' ghosts.  There are also a lot of strange, glowing red butterflies flying around the dark village, hence the name "Fatal Frame: Crimson Butterfly"

In summary, It's awesome.

10.Wolverine
9.Cynder
8.Isaac (Dead space)
7.master cheif
6. Spyro
5.Clank
4.Rayman
3.Harry Potter
2. Rachet
1.Alex mercer

if you don't agree. meh... i don't care... much anyway...

1. Lara Croft (She knows how to roll.)
2. GLaDOS (Hilarious to listen to during the boss battle with her.)
3. Spyro (He can sometimes be an annoying little brat)
4. Commander Keen (Old DOS game series of some kid with a plasma pistol and a space ship in his backyard)
5. Crash Bandicoot
6. Alex Steel (crazy headbanger in GH2 lol)
7. Psycho Mantis (Metal Gear Solid)
8. Sonic (He gets on my nerves sometimes)
9. Zelda (Basically has little personality, has a sword and a shield... and that it)
10. Mario (Some random Italian guy who can jump high and runs around alot)

Honorable Mentions: Guidebot (Descent 2 & 3), Sparks (TLoS, he acts like me...sorta), Starfox McCloud, Glover, and Sgt. Johnson (Halo series... even though he gets killed in Halo 1 [by accident] and Halo 3 [on purpose])

I love the first three Spyro games, but I just didn't find the characters that in-depth or interesting. They were all pretty flat and boring to me. Tales series however, does a fantastic job. Raven and Zelos especially were just so in-depth and had such inner conflict that they don't show on the surface of the character it is just amazing.

10.Bowser(mario series)
9.Wario(mario series)
8.Volteer(Spyro series)
7.Cyril(Spyro Series)
6.Ignitus(Spyro Series)
5.Luigi(Mario Series)
4.Yoshi(Mario Series)
3.Cynder(Spyro Series)
2.Mario or Spyro(can go either way)
1.Mario or Spyro(can go either way)

I've played final fantasy X now, not all the way through, but still.

I want to kill Seymour so badly. He just stands there with his whiney voice, hate him. Not a terrible character, I just hate him.